Chemistry in JEE Main is divided into Physical, Organic, and Inorganic Chemistry. Important topics in Physical Chemistry include Mole Concept, Chemical Equilibrium, Thermodynamics, Chemical Kinetics, and Electrochemistry. In Organic Chemistry, topics such as General Organic Chemistry (GOC), Hydrocarbons, Alcohols, Aldehydes and Ketones, Carboxylic Acids, and Biomolecules are frequently tested. In Inorganic Chemistry, important chapters include Chemical Bonding, Coordination Compounds, Periodic Table, p-Block Elements, and d-Block Elements. Many questions in Chemistry are directly based on NCERT textbooks, making them essential for preparation.